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Karl Tryggvason Selected Research

Transplantation

5/2023Pluripotent stem cell-derived committed cardiac progenitors remuscularize damaged ischemic hearts and improve their function in pigs.
1/2020Chemically defined and xenogeneic-free culture method for human epidermal keratinocytes on laminin-based matrices.
1/2018Culturing functional pancreatic islets on α5-laminins and curative transplantation to diabetic mice.
5/2006Recurrence of proteinuria following renal transplantation in congenital nephrotic syndrome of the Finnish type.

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Karl Tryggvason Research Topics

Disease

19Proteinuria
01/2017 - 02/2001
13Nephrotic Syndrome (Syndrome, Nephrotic)
01/2017 - 06/2000
9Neoplasms (Cancer)
10/2009 - 05/2002
8Kidney Diseases (Kidney Disease)
01/2020 - 02/2001
6Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal)
10/2021 - 02/2001
6Diabetic Nephropathies (Diabetic Nephropathy)
01/2020 - 01/2010
5Fibrosis (Cirrhosis)
10/2021 - 01/2006
5Nephrosis
01/2017 - 02/2001
5Inflammation (Inflammations)
01/2016 - 07/2004
5Hereditary Nephritis (Alport Syndrome)
11/2014 - 04/2000
5Lipoid Nephrosis (Glomerulonephritis, Minimal Change)
09/2014 - 03/2002
4Albuminuria
10/2021 - 01/2011
4Neoplasm Metastasis (Metastasis)
05/2011 - 06/2002
4congenital Nephrosis
11/2004 - 02/2001
3Infarction (Infarctions)
05/2023 - 01/2019
3Infections
10/2022 - 06/2009
3Hypoxia (Hypoxemia)
01/2018 - 01/2006
3Laminopathies
12/2012 - 05/2002
3Inborn Genetic Diseases (Disease, Hereditary)
02/2004 - 04/2000
3Nephritis
10/2003 - 04/2000
2Wounds and Injuries (Trauma)
01/2020 - 01/2004
2Renal Insufficiency (Renal Failure)
08/2015 - 10/2011
2Chronic Kidney Failure (Chronic Renal Failure)
08/2015 - 09/2012
2Disease Progression
11/2014 - 10/2007
2Ischemia
11/2014 - 01/2006
2Type 1 Diabetes Mellitus (Autoimmune Diabetes)
06/2014 - 08/2012
2Weight Gain
01/2014 - 03/2004
2Body Weight (Weight, Body)
12/2012 - 03/2004
2Craniofacial Abnormalities
06/2012 - 01/2003
2Carcinoma (Carcinomatosis)
10/2009 - 06/2002
2Pneumonia (Pneumonitis)
03/2007 - 07/2004
2Hearing Loss (Hearing Impairment)
10/2003 - 04/2000
2Membranous Glomerulonephritis (Membranous Nephropathy)
03/2002 - 02/2001
2IGA Glomerulonephritis (IGA Nephropathy)
03/2002 - 02/2001
1Myocarditis (Carditis)
10/2022
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2022
1Burns
01/2020
1Junctional Epidermolysis Bullosa (Epidermolysis Bullosa Letalis)
01/2020
1Teratoma (Teratoid Tumor)
01/2019
1Yellow Fever
12/2018
1Starvation
01/2018
1Necrosis
01/2018
1Pierson syndrome
01/2018
1Peritoneal Fibrosis
01/2017
1Wolf-Hirschhorn Syndrome
01/2017

Drug/Important Bio-Agent (IBA)

20nephrinIBA
01/2017 - 06/2000
18Proteins (Proteins, Gene)FDA Link
10/2022 - 02/2002
13Laminin (Merosin)IBA
01/2022 - 02/2002
5Heparitin Sulfate (Heparan Sulfate)IBA
11/2014 - 03/2004
4Protein Isoforms (Isoforms)IBA
01/2020 - 06/2002
4Matrix Metalloproteinases (MMPs)IBA
01/2017 - 05/2002
4Collagen Type IV (Type IV Collagen)IBA
11/2014 - 04/2000
4perlecanIBA
11/2014 - 03/2004
4Puromycin AminonucleosideIBA
09/2014 - 09/2007
4Scavenger Receptors (Scavenger Receptor)IBA
05/2013 - 07/2004
4IntegrinsIBA
05/2011 - 01/2006
3dendrinIBA
08/2015 - 08/2008
3AntibodiesIBA
10/2009 - 02/2002
3KalininIBA
11/2007 - 06/2002
3NPHS2 proteinIBA
11/2004 - 02/2002
2Streptozocin (Streptozotocin)FDA Link
01/2021 - 01/2016
2DNA (Deoxyribonucleic Acid)IBA
01/2020 - 07/2005
2Messenger RNA (mRNA)IBA
01/2017 - 02/2001
2LipopolysaccharidesIBA
01/2016 - 01/2009
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2014 - 01/2006
2AlbuminsIBA
06/2014 - 01/2011
2AutoantibodiesIBA
05/2013 - 10/2007
2Matrix Metalloproteinase 14 (MT1-MMP)IBA
06/2012 - 01/2003
2laminin 10IBA
05/2011 - 11/2007
2CollagenIBA
12/2010 - 10/2009
2Blocking AntibodiesIBA
10/2009 - 11/2007
2CytokinesIBA
06/2009 - 07/2004
2LipidsIBA
07/2008 - 03/2007
2Lamin Type A (Lamin A)IBA
07/2005 - 05/2002
2laminin 8IBA
04/2005 - 06/2004
1Proteasome Endopeptidase Complex (Proteasome)IBA
10/2022
1Pattern Recognition ReceptorsIBA
10/2022
1Leucine (L-Leucine)FDA Link
10/2022
1NucleotidesIBA
10/2022
1Peptide Hydrolases (Proteases)FDA Link
10/2022
1HemosiderinIBA
10/2021
1Protein Kinase CIBA
01/2020
1Recombinant ProteinsIBA
01/2019
1InterferonsIBA
12/2018
1VaccinesIBA
12/2018
1Attenuated VaccinesIBA
12/2018
1Mechanistic Target of Rapamycin Complex 1IBA
01/2018
1SuspensionsIBA
01/2018
1Tyrosine (L-Tyrosine)FDA Link
01/2018
1Transforming Growth Factors (Transforming Growth Factor)IBA
01/2017
1Biocompatible Materials (Biomaterials)IBA
01/2017
1Semaphorins (Semaphorin)IBA
01/2016
1MorpholinosIBA
01/2015
1Heparan Sulfate Proteoglycans (Heparan Sulfate Proteoglycan)IBA
11/2014
1Doxorubicin (Adriamycin)FDA LinkGeneric
09/2014

Therapy/Procedure

6Therapeutics
01/2020 - 03/2009
4Transplantation
05/2023 - 05/2006
2Kidney Transplantation
09/2012 - 05/2006
1Islets of Langerhans Transplantation
01/2018
1Renal Replacement Therapy (Therapies, Renal Replacement)
08/2015